Now, as part of AbbVie, the programme is well positioned to move into late-stage clinical development.. AbbVie Bolsters Neuro Platform with $1B Syndesi Buy On Mar 2, 2022. Transform. The collaborative effort by Novo Seeds and UCB Pharma - alongside a syndicate of Belgian and international investors - enabled Chief Executive Officer Jonathan Savidge and his team to focus on progressing the first-in-class synaptic vesicle protein 2A (SV2A) programme into clinical Phase 1b studies. Confo has attracted an international team of accomplished scientists and business professionals to deploy its innovative . Syndesi Therapeutics - Crunchbase Company Profile & Funding Syndesi Therapeutics serves customers worldwide. Rappta's proprietary tools and understanding of the target allow us to therapeutically reactivate PP2A, a critical enzyme . The Syndesi Therapeutics annual revenue is estimated at < 1M. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Syndesi Therapeutics is one of several Novo Seeds portfolio companies focused on developing better treatments for CNS disorders, an area of significant unmet medical need. Acquiring Organization: AbbVie AbbVie is a pharmaceutical company that discovers, develops, and markets both biopharmaceuticals and small molecule drugs. AbbVie Acquires Syndesi Therapeutics, Strengthening - Yahoo! 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About Syndesi Therapeutics. We're on it. Syndesi Therapeutics SA, a clinical stage biotechnology company developing novel modulators of the synaptic vesicle protein SV2A for the treatment of cognitive impairment, announces results from two Phase I studies of its lead compound SDI-118, supporting further development of this promising molecule. March 01, 2022. With an upfront payment of $130 million, AbbVie gains Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. AbbVie buys Syndesi Therapeutics for up to $1bn - Silicon Republic The UK Life Sciences team advised Syndesi Therapeutics and its shareholders on Syndesi's acquisition by AbbVie (NYSE: ABBV). Novo Holdings Portfolio Company Syndesi Therapeutics acquired by AbbVie V-Bio Ventures - Capital for Life Sciences Syndesi Therapeutics SA operates as a biotechnology company. Criteria. I am delighted with the announcement of this deal. In this process the team has added significant insights into the biology of SV2A and the mechanism of action of the Companys lead program SDI-118. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic . Other executives include John Kemp, Chief Scientific Officer; Torsten Madsen, Chief Medical Officer and 4 others. Syndesi Therapeutics SA Information | Syndesi Therapeutics SA Profile As one of the leading pharmaceutical companies in CNS drug development globally, AbbVie makes the perfect partner to maximize the potential benefit of Syndesi's lead candidate, SDI-118, for the treatment of cognitive impairment across multiple diseases.". Click Manage settings for more information and to manage your choices. Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases. The investment in Syndesi is an integral part of Novo Seeds' approach to new venture formation by co-leading spinouts from pharmaceutical companies based on assets that are no longer in-line with the corporation's overall strategy. Syndesi | VentureRadar It has been a pleasure to partner with Novo Seeds . Syndesi is investigating the potential of these molecules to improve cognition in diseases such as Alzheimer's Disease and other dementias, as well as other conditions such as major depression and cognitive impairment associated with schizophrenia. Now, as part of AbbVie, the programme is well positioned to move into late-stage clinical development.". Brussels, Belgium - February 1st, 2018 - The creation of Syndesi Therapeutics ('Syndesi') was announced today as the result of a partnership between UCB and a syndicate of Belgian and international investors.The investor syndicate is led by Novo Seeds and Fountain Healthcare together with Johnson & Johnson Innovation - JJDC, Inc. (JJDC), V-BIO Ventures, the Walloon Investment Fund . It has been a pleasure to partner with Novo Seeds, UCB and our other investors to investigate the potential of SDI-118 in early clinical studies. AbbVie Acquires Syndesi Therapeutics - World Pharma Today Syndesi Therapeutics is developing molecules that modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Syndesi Therapeutics SA - Company Profile and News In addition to Syndesi Therapeutics Novo Seeds has launched four other companies in the neuroscience space including Muna Therapeutics (neurodegeneration), NMD Pharma (neuromuscular disorders), Hoba Therapeutics (Pain), and Avilex Pharma (Acute Ischemic Stroke). Target. Copenhagen, Denmark Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics (Syndesi) has been acquired by AbbVie (NYSE: ABBV) for up to US$1 billion in total deal value with US$ 130 million upfront. With the support of our investors and other stakeholders, Syndesi's goal is to demonstrate the potential of these molecules to reduce the symptoms of . Bone Therapeutics has a broad portfolio of innovative allogeneic cell therapy solutions across a range of indications. Morten Graugaard Dssing, Board Director of Syndesi and Partner at Novo Holdings, said: "Spin-out ventures from pharmaceutical companies are an integrated part of Novo Seeds' company creation strategy, where we aim to add significant strategic and operational support to the spin-out process. The Company specializes in neurology drug discovery to develop potential therapeutics in cognitive disorders. They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. The Company's approach is aimed at treating Alzheimer's Disease and other disorders with cognitive impairment. Our distinctive Probody therapeutics are progressing through the clinic with the promise of unlocking the full potential of more potent, less toxic anti-cancer medications. Developing novel SV2A modulators as potential treatments for cognitive impairment | Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Syndesi Therapeutics offers modulators to improve cognition in diseases such as alzheimer's disease and other conditions causing cognitive impairment. from 8 AM - 9 PM ET. Provides strong support for the initiation of further clinical trials in cognitive impairment. Syndesi Therapeutics is a private company that has been in the industry for 4 years. Syndesi is investigating the potential of these molecules to improve cognition in diseases such as Alzheimer's Disease and other dementias, as well as other conditions such as major depression and cognitive . Go to Syndesi Therapeutics was established to develop a series of novel, pro-cognitive small molecule SV2A modulators licensed from UCB. Medical. The company's drugs can modulate the synaptic vesicle protein to handle the transmission between neurons in the brain to effectively treat Alzheimer's and other disorders with cognitive impairment, enabling healthcare providers to treat these diseases with the right . About Syndesi Therapeutics. Novo Holdings A/S is a private limited liability company wholly owned by the Novo Nordisk Foundation. AbbVie announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. AbbVie expands neuroscience portfolio with Syndesi acquisition To get there, he's had to face down many challenges, including a fashion industry that's often held back Black designers. For further information Syndesi Acquired by Abbvie for up to $1 Billion Syndesi Therapeutics - Overview, News & Competitors | ZoomInfo.com About Syndesi Therapeutics. ABBV ie (NYSE: ABBV) today announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand ABBV ie's neuroscience portfolio. Syndesi Therapeutics's Chief Executive Officer is Jonathan Savidge. MT-2000 is a class of agents that are designed to precisely convert pro-inflammatory M1 Macrophages to anti-inflammatory M2 macrophages. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). We worked closely with the Syndesi team and our co-investors through the Companys early development and we are incredibly proud of the progress made. It is the holding company of the Novo Group, comprising Novo Nordisk A/S and Novozymes A/S, and is responsible for managing the Novo Nordisk Foundation's assets.Novo Holdings is recognised as a leading international life science investor, with a focus on creating long-term value. Celebrity tailor and designer Rich Fresh has made a name for himself in Los Angeles as a luxury athleisure designer. Home - CytomX Jonathan Savidge, Chief Executive Officer, Syndesi Therapeutics, said: "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of . Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Syndesi Therapeutics Company Profile: Acquisition & Investors | PitchBook Syndesi Therapeutics was established to develop a series of novel, pro-cognitive small molecule SV2A modulators licensed from UCB. Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world. Jonathan Savidge and the Syndesi team have developed a portfolio of novel SV2A modulators to treat synaptic transmission deficits associated with cognitive dysfunction across a range of neuropsychiatric and neurodegenerative disorders such as Alzheimers Disease, Parkinsons Disease, schizophrenia, and depression. UCB and investor syndicate led by Novo Seeds launch Syndesi Developer of drug molecules designed to treat cognitive impairment. We look for innovative and transformational technologies with high societal and/or environmental impact potential, in line with the U.N. Novo Holdings Syndesi Therapeutics Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. When typing in this field, a list of search results will appear and be automatically updated as you type. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American. There is a major unmet need for new therapies that can . Syndesi Therapeutics Syndesi Therapeutics develops a drug candidate for the treatment of consecutive cognitive disorders of various neurological conditions. Syndesi was created in 2018 as the result of a close collaboration between Novo Seeds, the company creation arm of Novo Holdings, and UCB Pharma, the Belgium-based global pharmaceutical company. Syndesi Therapeutics raised $21254941 on 2018-02-15 in Series A. Novo Seeds Novo Seeds identifying, building and investing in exceptional startups. Information about your device and internet connection, like your IP address, Browsing and search activity while using Yahoo websites and apps. Syndesi Therapeutics is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment seen in multiple CNS disorders, including Alzheimers Disease, schizophrenia and depresson. In addition to Syndesi Therapeutics Novo Seeds has launched four other companies in the neuroscience space including Muna Therapeutics (neurodegeneration), NMD Pharma (neuromuscular disorders), Hoba Therapeutics (Pain), and Avilex Pharma (Acute Ischemic Stroke). AbbVie will pay Syndesi's shareholders a $130 million upfront payment with the potential for Syndesi's shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. See the full leadership team at Craft. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic . Regulating synaptic transmission represents . Series A - Syndesi Therapeutics - 2018-02-15 - Crunchbase Confo Therapeutics' unparalleled technology stabilizes functional conformations of GPCRs (G protein-coupled receptors) to uncover a wide range of previously inaccessible drug targets. +1 more. Syndesi Therapeutics | CipherBio AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio.. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Novo Holdings also manages a broad portfolio of diversified financial assets. As a life science investor, Novo Holdings provides seed and venture capital to development-stage companies and takes significant ownership positions in growth and well-established companies. Description. I am delighted with the announcement of this deal. Type Company Type For Profit. Macrophage Therapeutics, Inc. In this process the team has added significant insights into the biology of SV2A and the mechanism of action of the Company's lead program SDI-118. Cision Distribution 888-776-0942 Jonathan Savidge, Chief Executive Officer, Syndesi Therapeutics, said: "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of SDI-118 in a range of neurologic diseases. Syndesi Therapeutics | 835 followers on LinkedIn. AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Syndesi Therapeutics is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Find out more about how we use your information in our privacy policy and cookie policy. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders . AbbVie Acquisition Strengthens Its Neuroscience Portfolio - Yahoo! Syndesi was created in 2018 as the result of a close collaboration between Novo Seeds, the company creation arm of Novo Holdings, and UCB Pharma, the Belgium-based global pharmaceutical company. We, Yahoo, are part of the Yahoo family of brands. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Portfolio The only daily news program focused exclusively on technology, innovation and the future of business from San Francisco. Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by . It has been a pleasure to partner with Novo Seeds, UCB and our other investors to investigate the potential of SDI-118 in early clinical studies. The company currently specializes in the Biotechnology area. Morten Graugaard Dssing, Board Director of Syndesi and Partner at Novo Holdings, said: Spin-out ventures from pharmaceutical companies are an integrated part of Novo Seeds company creation strategy, where we aim to add significant strategic and operational support to the spin-out process.